Multi-System and Multi-Animal Monitoring for Identification of Seizures, Arrhythmias, and Apnea
Event Details
Course introduction: This session, presented by Dr. David Auerbach, an assistant Professor of Pharmacology at SUNY Upstate Medical University will discuss the development of a methodology to evaluate the neuro-cardiac-respiratory
Event Details
Course introduction:
This session, presented by Dr. David Auerbach, an assistant Professor of Pharmacology at SUNY Upstate Medical University will discuss the development of a methodology to evaluate the neuro-cardiac-respiratory function. Specifically, attendees will learn to about a non-invasive system to simultaneously acquire video-EEG-ECG-oximetry-capnography recordings from conscious restrained animals. This novel recording system establishes a platform to test the efficacy and safety of therapeutics and can capture the complex cascade of multi-system events that culminate in sudden death. In addition to outlining the methodology for data acquisition, the discussion will include the analytical approaches for examining neuro-cardiac-respiratory function and pathologies.
Learning Objectives:
At the conclusion of this seminar the participants will be able to:
- It is critical to take a multi-system approach to examining the cascade of systemic changes that surround seizures.
- Discuss the development of a non-invasive system to acquire simultaneous video-EEG-ECG- oximetry-capnography recordings from conscious restrained animals.
- Learn about analytical approaches for examining neuro-cardiac-respiratory function and pathologies.
Speakers for this event
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Dr. David Auerbach
Dr. David Auerbach
Ph. D
David Auerbach, PhD, is an Assistant Professor of Pharmacology at SUNY Upstate Medical University. His biomedical research training began during his undergraduate studies at Skidmore College, and masters training from the Department of Physiology & Biophysics at Case Western Reserve University. He conducted his doctoral studies in the laboratory of Dr. Jose Jalife at Upstate Medical University, where he provided insights into the substrates (structural heterogeneities) and triggers (alterations in ion channel expression and function) for arrhythmias. Subsequently, he completed a postdoctoral fellowship at the University of Michigan in Dr. Lori Isom’s laboratory. He demonstrated that in severe genetic forms of epilepsy, there are not only alterations in electrical function in the brain, but also in the heart, resulting in both seizures and cardiac arrhythmias. In 2014 Dr. Auerbach joined University of Rochester Medical Center and, under the mentorship of Drs. Robert Dirksen and Arthur Moss, he began developing an independent line of research. He has shown that it is important to take a multi-system approach to studying electrical diseases of both the brain and heart. He is actively investigating the prevalence, risk factors, and mechanisms for the multi-system cascade of events that lead to Sudden Unexpected Death in Epilepsy Patients (SUDEP).
Ph. D
Time
(Thursday) 11:00 am - 12:00 pm EST
Location
ONLINE eSeminar
