Pressure reactivity index for early neuroprognostication in poor-grade subarachnoid hemorrhage

Jason J. Chang, David Kepplinger, E. Jeffrey Metter, Daniel R. Felbaum, Jeffrey C. Mai, Rocco A. Armonda, Edward F. Aulisi

Journal of the Neurological Sciences, Volume 450, Article 120691, July 15, 2023.  Epub May 24, 2023

Background

Pressure reactivity index (PRx) utilizes moving correlation coefficients from intracranial pressure (ICP) and mean arterial pressures to evaluate cerebral autoregulation. We evaluated patients with poor-grade subarachnoid hemorrhage (SAH), identified their PRx trajectories over time, and identified threshold time points where PRx could be used for neuroprognostication.