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Frederick A Zeiler, Ari Ercole, Manuel Cabeleira, Marco Carbonara, Nino Stocchetti, David K Menon, Peter Smielewski, Marek Czosnyka
Background
Monitoring cerebrovascular reactivity in adult traumatic brain injury (TBI) has been linked to global patient outcome. Three intra-cranial pressure (ICP)-derived indices have been described. It is unknown which index is superior for outcome association in TBI outside previous single-center evaluations. The goal of this study is to evaluate indices for 6- to 12-month outcome association using uniform data harvested in multiple centers.
