Electroencephalographic response to deep hypothermic circulatory arrest in neonatal swine and humans

 

Constantine D Mavroudis, Kobina G Mensah-Brown, Tiffany S Ko, Timothy W Boorady, Shavonne L Massey, Nicholas S Abend, Susan C Nicolson, Ryan W Morgan, Christopher E Mascio, J William Gaynor, Todd J Kilbaugh, Daniel J Licht

 

Background

Piglets are used to study neurologic effects of deep hypothermic circulatory arrest (DHCA), but no studies have compared human and swine electroencephalogram (EEG) responses to DHCA. The importance of isoelectricity before circulatory arrest is not fully known in neonates. We compared the EEG response to DHCA in human neonates and piglets.