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This session, presented by Dr. David Auerbach, an assistant Professor of Pharmacology at SUNY Upstate Medical University will discuss the development of a methodology to evaluate the neuro-cardiac-respiratory function. Specifically, attendees will learn to about a non-invasive system to simultaneously acquire video-EEG-ECG-oximetry-capnography recordings from conscious restrained animals. This novel recording system establishes a platform to test the efficacy and safety of therapeutics and can capture the complex cascade of multi-system events that culminate in sudden death. In addition to outlining the methodology for data acquisition, the discussion will include the analytical approaches for examining neuro-cardiac-respiratory function and pathologies.