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| Cerebral and Renal Oxygenation in Infants Undergoing Laparoscopic Gastrostomy Tube Placement |
Cerebral and Renal Oxygenation in Infants Undergoing Laparoscopic Gastrostomy Tube Placement
Amanda Muñoz, John Tan, Andrew Hopper, Rosemary Vannix, Harmony Carter, Michelle Woodfin, Arlin Blood, Joanne Baerg
Abstract
Aim: The aim of this study was to evaluate the effects of a carbon dioxide pneumoperitoneum on cerebral and renal oxygenation and oxygen extraction, in a cohort of infants from the neonatal intensive care unit, undergoing laparoscopic gastrostomy.
Methods: After institutional review board approval, between February 2018 and June 2019, infants 0-3 mo corrected age, undergoing laparoscopic gastrostomy tube placement, were included. Strict exclusion criteria created a homogeneous cohort. Cerebral and renal tissue oxygen saturation (rSO2) by near-infrared spectroscopy, skin surface oxygen saturation (SpO2), by pulse oximetry, and amplitude-integrated electroencephalography were measured. Monitoring was divided into preoperative, intraoperative and postoperative time periods. Cerebral and renal fractional tissue oxygen extraction was calculated using arterial (SpO2) and tissue oxygen saturation (rSO2): (SpO2-rSO2SpO2)X100. Data were averaged into one-minute epochs and significant changes from baseline during the intraoperative and postoperative periods were detected using one-way analysis of variance with repeated measures.
