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A female infant born at 38+4 weeks gestation with a birth weight of 3170 grams. The mother was G1P0. She was admitted for induction at 38+4 weeks gestation because of pregnancy induced hypertension. On rupture of the membranes there was blood loss and on CTG a fetal tachycardia was seen. An emergency caesarean section was performed and during the resuscitation the infant had profound bradycardia with no spontaneous breathing effort. After 5 inflation breaths the heart rate increased and after 10 minutes she was breathing spontaneously but with an irregular breathing pattern. Apgar scores were 2, 5 and 7 at 1, 5 and 10 minutes respectively. She was admitted to the neonatal unit in an outlying hospital where she stabilized quickly. Her first glucose level was 3.6 mmol/L and she had a capillary sample lactate of 11.2 mmol/L. Around 12 hours after birth she had an incident of bradycardia, followed by a drop of oxygen saturation and thereafter clinical seizure like activity involving both arms and legs. A loading dose of phenobarbitone (20 mg/kg) was given. Ten hours later she developed clinical seizures again with movements of her right arm and a drop in oxygen saturation. Another dose of phenobarbitone was given and she was transported to our NICU for further cerebral monitoring and investigation.
Please download following .PDF to view the full clinical case study.
Dr. Linda van Rooij
Department of Neonatology
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Upcoming LIVE eSeminars
December
18dec11:00 am12:00 pmHow to Interpret SEEG RecordingsLive eSeminar
Event Details
SEEG interpretation relies on the compartmentalization of the epileptogenic region into ‘lesional’, ‘irritative’, and ‘epileptogenic’ zones to differentiate interictal and ictal abnormalities. This approach avoids any bias in localization, i.e.
Event Details
SEEG interpretation relies on the compartmentalization of the epileptogenic region into ‘lesional’, ‘irritative’, and ‘epileptogenic’ zones to differentiate interictal and ictal abnormalities. This approach avoids any bias in localization, i.e. causing confusion between lesion and epilepsy, or between spikes and seizures. We will review what these different terms mean, which are the relevant biomarkers that help to differentiate these 3 zones, what are their causal relationship, and how their identification then allows, through their 3D representation, a careful individualized planning of the surgical resection.
Learning Objectives:
- Understand that SEEG interpretation starts with electrode implantation
- Identify relevant paroxysmal activities
- Identify relevant seizure onset patterns
- Understand how to use stimulation
1.0 CEU is available through ASET
Speakers for this event
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Prof. Philippe Kahane
Prof. Philippe Kahane
Philippe Kahane, MD, PhD, is a neurologist and neurophysiologist, Hospital Practitioner and University Professor at Grenoble-Alpes Hospital & University, France. He is heading the Clinical Neurosciences Axis of Grenoble Hospital. He is acknowledged as an international expert on presurgical assessment of drug-resistant epilepsies in adults and children, including SEEG recordings. The area of research covers various fields in epileptology and physiology in humans, including the characterization of epileptogenic networks using SEEG recordings and stimulation, the assessment of physiological networks by analysing SEEG oscillatory responses to different cognitive tasks, and the implementation of novel surgical therapies such as deep brain stimulation. He is Associate Editor of the international journal Epileptic Disorders, and is co-director of the annual Asian, European and North-American SEEG Training Courses. He is author or co-author of over 280 articles in international journals indexed in Medline, and has been invited to give presentations in over 320 international seminars and meetings.
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December 18, 2025 11:00 am - 12:00 pm(GMT-05:00)

