HFOs Clinical Relevance in Epilepsy

Lawrence J. Hirsch, M.D. is Professor of Neurology, Chief of the Division of Epilepsy and EEG, and Co-Director of the Comprehensive Epilepsy Center, all at Yale University. He has held leadership positions in the American Clinical Neurophysiology Society (ACNS), American Epilepsy Society, American Academy of Neurology, and the Epilepsy Foundation, and is lead author of the 2012 and 2021 ACNS guidelines on critical care EEG terminology. He is founder and former chair of the Critical Care EEG Monitoring Research Consortium, which now includes more than 50 centers, and co-chair of the medical advisory board of the NORSE Institute. He has been an active researcher throughout his career, having published more than 200 peer-reviewed manuscripts and more than 100 reviews, editorials or book chapters on topics including status epilepticus, all aspects of EEG including intracranial recordings and brain monitoring in the critically ill, brain stimulation, epilepsy surgery, seizure clusters, rescue medications, sudden death in epilepsy (SUDEP), and anti-seizure medication use. He has won multiple teaching awards and is co-author of the first-ever atlas on EEG in critical care.

With over 30 years of experience, Sanjeev is an award winning author, editor and reviewer, researcher, instrument design engineer, teacher, and clinical expert in the EMG field. He has delivered lectures, workshops and seminars in over 25 countries at universities, hospitals and EMG conferences. As an editor, Sanjeev started the “EMG on DVD” educational series. In collaboration with other clinicians, he developed Motor Unit Number Index (MUNIX) along with Multi-Motor unit Analysis (MMA) and Turns & Amplitude (TA) methods available on Natus EMG systems. His primary research interest is in Automatic analysis of EMG signals, Modeling EMG signals and Technical aspects of EMG waveforms. Sanjeev is currently a Senior Consultant at Natus Medical. Sanjeev is also Adjunct Professor of Neurology at Medical College of Wisconsin.

Mark Quigg, MD, received neurology training at the University of Virginia and neuroscience training at the Karolinska Institute in Stockholm, Sweden. He specializes in the evaluation and treatment of difficult-to-control seizures and the neurological aspects of sleep medicine. He is the medical director of the electroencephalography and intensive monitoring laboratories and is an expert in using these tools to evaluate epilepsy, sleep disorders and disorders with similar symptoms. He is nationally recognized for his clinical practice and research. He holds national offices, including on the neurology board and professional societies for neurology and epilepsy.
Dr. Quigg enjoys living in Charlottesville and is an avid runner and cyclist. He is also a woodworker and has put significant sweat equity into his old house in downtown Charlottesville. He has two children with his wife, Lotta.

Julie Pagel is a neurocritical care nurse specialist at Natus. She has clinical practice experience in both medical and neurosurgical intensive care settings, totaling over 12 years along with serving as a neuroscience divisional educator at a level 1 trauma, comprehensive stroke hospital in Charlotte, NC. She also served as adjunct faculty at University of North Carolina at Charlotte for 8 years. She is currently responsible for the education of clinicians including curriculum and competency development, instructional design, and multi-modality delivery. Her Master’s degree specializes in nursing education. And her doctoral work investigated the effect of early mobility on functional ability of stroke patients post-TPA. She has presented her work nationally on topics ranging from adult and pediatric stroke, creation of a neuro-intermediate unit, interprofessional education, innovative teaching strategies, simulation, and cultivating clinical reasoning. She has published on nurse preceptors and new graduate nurses’ transition into practice along with the impact of COVID-19 on new graduate nurses’ success. She is passionate about the promotion of neuroscience nursing and neurocritical care through involvement with the American Association of Neuroscience Nurses, including serving on the board of directors. 

Louis Maillard MD, PhD has been heading since 2005 the Patrick Chauvel epileptology unit at the Regional University Hospital of Nancy, which is a tertiary French and European Reference Center for rare and drug refractory epilepsies (ERN EPICARE). He is Professor of Neurology at Lorraine University and member of the Clinical and Neuroscience Research Team, Lorraine University, Centre National de la Recherche Scientifique, UMR 7365. He is also heading the Scientific Board of the French Clinical Neurophysiology Society and member of the ILAE Task Force on Diagnostic Methods/EEG. Louis Maillard did a clinical fellowship in the Marseille epileptology Unit  from 2003 to 2005 and a PhD in neuroscience at the university of Marseille under the supervision of Pr Patrick Chauvel and Catherine Chauvel. His research interests and publications have focused on drug-resistant epilepsies with several purposes: (1) improving the delineation of epileptogenic zone based on both Stereo-Electroencephalography and on Electrical Source Imaging; (2) Improving the post-surgical cognitive outcome, especially in language and visual recognition, using electrical cortical stimulation, intra-cerebral evoked potentials, cortico-cortical evoked potentials. Louis Maillard has been a tutor and faculty in numerous international workshops and congresses on Stereo-Electroencephalography and drug resistant epilepsies and will be chairing the special interest group of the AES dedicated to SEEG in 2024.

Sushma is the Lead Consultant Paediatric Clinical Neurophysiologist at Evelina London Children’s Hospital and an Honorary Consultant at King’s College Hospital, London. Her specialist interests include Neonatal and Paediatric EEG and evaluation of children for epilepsy surgery. She is the International Secretary of the British Society of Clinical Neurophysiology (BSCN) and was a member of ILAE Neurophysiology taskforce in 2017 for the role of EEG in the diagnosis and classification of epilepsy syndromes. She is a faculty on the neonatal and paediatric ILAE EEG courses. She is a member of the King’s Healthcare Partners team that won the NHS Innovation Challenge Prize for developing home video EEG telemetry in the UK.

Wissenschaftliche Leitung: PD Dr. med. Peter Trillenberg, Klinik für Neurologie – Forschung & Lehre, Universität zu Lübeck