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Spreading depolarization monitoring in neurocritical care of acute brain injury |
Spreading depolarization monitoring in neurocritical care of acute brain injury
Jed A Hartings
Abstract
Purpose of review: Spreading depolarizations are unique in being discrete pathologic entities that are well characterized experimentally and also occur commonly in patients with substantial acute brain injury. Here, we review essential concepts in depolarization monitoring, highlighting its clinical significance, interpretation, and future potential.